AIM: To study the relationship between the behavior of shuttle-box avoidance conditioning ( SAC) and the development of cholinergic and adrenergic transmitter systems. 目的:探讨幼鼠脑内胆碱能和肾上腺素能递质系统的发育与梭箱回避学习行为(shuttle-boxavoidanceconditioning,SAC)的关系。
Appearance of withdrawal reactions may associated with pharmacological effects on serotonin, dopamine, norepinephrine, GABA and cholinergic transmitter in central nervous system. 撤药反应的出现可能与药物对中枢神经系统中血清素、多巴胺、去甲肾上腺素、GABA、胆碱能类递质系统的影响有关。
Hypothalamic endogenous cholinergic transmitter can produce negative chronotropic and positive inotropic response to myocardium. Hypothalamic TRH mediates cardiac function maybe partly through cholinergic M receptor. 下丘脑内源性胆碱能递质对心脏有正性变时但负性变力的作用,下丘脑TRH调节心功能可能部分通过胆碱能M受体通路。
The pathogenesis of vascular cognitive impairment is considered mainly as the low content cholinergic transmitter, lacking supporting experimental studies on other mechanisms. 对于血管性认知障碍的发病机理,主要认为胆碱能递质的含量低下,而其他的发病机理缺乏相应的实验研究。